Dr Hayley Newton

Group Leader
Department of Microbiology and Immunology
University of Melbourne

hnewton@unimelb.edu.au

Research Activities

Research in our laboratory is focused on understanding the interaction between intracellular bacterial pathogens and the human host cell. We study Coxiella burnetii and Legionella species. These human pathogens establish very different vacuolar niches within the host yet they both employ the Dot/Icm Type IV Secretion System to achieve intracellular replication. We focus on the cohorts of effector proteins that mediate intracellular survival and replication of these pathogens

Techniques/Expertise

Genetic manipulation of pathogenic bacteria
Investigation of molecular aspects of host-pathogen interaction
Immunofluorescence microscopy
Protein-protein interactions

Collaborations

Prof Elizabeth Hartland
Prof Craig Roy
Dr Dario Zamboni
Dr Fiona Sansom

Genetically Modified Organisms

Coxiella burnetii, Legionella pneumophila, Legionella longbeachae

Other Lab Members

Dr Patrice Newton
Chen Ai Khoo
Eleanor Latomanski
Miku Kuba
Bhavna Padmanabhan
Laura Fielden
Nicole Lau
Yi Wei Lee

Other members with similar research interests

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A/Prof Ashley Mansell

Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research SEE FULL PROFILE >

Prof Colby Zaph

Department of Biochemistry and Molecular Biology Monash University SEE FULL PROFILE >

A/Prof Wai-Hong Tham

Infection and Immunity Division Walter and Eliza Hall Institute of Medical Research SEE FULL PROFILE >

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