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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Ms Antara Ghoshal

Dr Nicole De Weerd

Dr Ben Croker

Dr Ashraful Haque

Prof Ana Traven

A/Prof Ashley Mansell

A/Prof Mark Wright

Dr Catherine Kennedy

Prof Alister Ward

Mr Stuart Lee

Miss Michelle Clark

Dr Holly Anderton

Prof Gabrielle Belz

Associate Professor Michelle Tate

Prof Tim Stinear

Prof Stephen Turner

Miss Rachel Peiris

Miss Kathryn Prame Kumar

Dr Alyssa Barry

Prof Jason Mackenzie

A/Prof Mark Chong

Dr Sara Klose

Dr Dominic De Nardo

Prof Roger Nation

Dr Hani Hosseini Far

Dr Bernadette Jones-Freeman

Dr Latasha Abeynaike

Dr KE TANG

Dr Rebecca Gorrell

Dr Howard Yim

Prof Steven Gerondakis

A/Prof Kumar Visvanathan

Dr Tony Sadler

Prof Jian Li

Dr Marina Harper

A/Prof Aaron Irving

Dr Kate Jeffrey

Adjunct Prof Kathryn Holt

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Dr Prasad Paradkar

Dr Niamh Mangan

Dr Kelly Wyres

Dr Scott Mueller

Dr Grant Jenkin

Dr Louis Schofield

Dr Helen Stoelting

Dr Tom Brodnicki

Dr Kristie Jenkins

Mr Douglas Gaskarth

Prof Bill Heath

A/Prof Anna Coussens

Dr Jim Harris

A/Prof Motti Gerlic

Dr Rutger Roring

Dr Seth Masters

Dr Simon Royce

Dr Carla Bianca Victorio

Ms Sarah Rosli

Ms Madeleine Wemyss

Miss Cassandra Stanton

A/Prof Michael Gantier

Dr Dieter Bulach

Dr Jiyao Gan