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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Dr Tony Sadler

Dr Greg Moseley

Prof Michael Hickey

Dr Patrick Reading

Prof Tim Stinear

Dr Rutger Roring

Dr Bernadette Jones-Freeman

Dr Helen Stoelting

Dr Keith Al-Hasani

Dr Hani Hosseini Far

Prof Ana Traven

Miss Michelle Clark

Dr Rebecca Gorrell

Dr Catherine Kennedy

Prof Roger Nation

Prof Gabrielle Belz

Adjunct Prof Kathryn Holt

Prof Di Yu

Dr Seth Masters

Dr Latasha Abeynaike

Dr Wenyi Li

Dr Dieter Bulach

Dr Boris Novakovic

Dr Douglas Gaskarth

A/Prof Michael Gantier

Prof Fabienne Mackay

A/Prof Motti Gerlic

Dr Alice West

Miss Rachel Peiris

Mrs Sheila Nankoberanyi

Miss Kathryn Prame Kumar

Prof Alister Ward

Dr Nicole De Weerd

Dr Jim Harris

Prof Bill Heath

Dr Amy Chung

A/Prof Aaron Irving

Prof Steven Gerondakis

Dr Prasad Paradkar

Dr Niamh Mangan

Dr Louis Schofield

Dr Alyssa Barry

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Associate Professor Michelle Tate

Dr Tom Brodnicki

A/Prof Anna Coussens

Dr Holly Anderton

Dr KE TANG

Prof Stephen Turner

Prof Paul Hertzog

Dr Alison West

Dr Scott Mueller

Dr Kristie Jenkins

Dr Sammy Bedoui

Dr Matt Firth

Dr Simon Royce

Dr Thomas Angelovich

Prof Jason Mackenzie

Prof Bryan Williams

Dr Le Son Tran

Miss Cassandra Stanton

A/Prof Kumar Visvanathan

Prof Jian Li